Stroke Prevention Trials
These trials are actively seeking patients for enrollment. Generally, patients must have had neurologic symptoms within the past 3-6 months. In some studies, screening blood tests are needed prior to enrollment. If you are interested in participating in these studies, please contact the Stanford Stroke Center by email: .(Please note: individual patient treatment advice cannot be given).
COSS (Carotid Occlusion Stroke Study)
A NIH sponsored trial of patients who have experienced a symptomatic carotid occlusion, who by PET scan posess abnormal oxygen extraction. Inclusion criteria coming soon.
Closure I
A Trial To Evaluate The Safety And Efficacy Of An Investigational Septal Closure System Versus Best Medical Therapy In Patients With A Stroke And/Or Transient Ischemic Attack Due To Presumed Paradoxical Embolism Through A Patent Foramen Ovale
Click here for inclusion criteria
We are no longer enrolling for the following trials:
PRoFESS: Prevention Regimen for Effectively Avoiding Second Strokes
Aggrenox, clopidogrel, and aspirin are all approved for stroke prevention in those who have already had a recent stroke and the PRoFESS trial is designed to directly compare the efficacy and safety of Aggrenox with clopidogrel in the reduction of recurrent stroke. The trial will also determine if treatment with the angiotensin receptor blocker Micardis produces an effective reduction in the risk of recurrent stroke compared to treatment with placebo on top of standard treatment.
